D.G. Monrads liberale manifest fra 1839

Op-cbio160073 1832..1839

Motivation: Large-scale gene expression profiling has been widely used to characterize cellular states in response to various disease conditions, genetic perturbations, etc. Although the cost of whole-genome expression profiles has been dropping steadily, generating a compendium of expression profiling over thousands of samples is still very expensive. Recognizing that gene expressions are ofte...

Ddh197 1839..1848

Human SCO1 and SCO2 are paralogous genes that code for metallochaperone proteins with essential, but poorly understood, roles in copper delivery to cytochrome c oxidase (COX). Mutations in these genes produce tissue-specific COX deficiencies associated with distinct clinical phenotypes, although both are ubiquitously expressed. To investigate the molecular function of the SCO proteins, we chara...

Dev121970 1831..1839

The current view of skeletal patterning fails to explain the formation of sesamoid bones. These small bones, which facilitate musculoskeletal function, are exceptionally embedded within tendons. Although their structural design has long puzzled researchers, only a limitedmodel for sesamoid bone development has emerged. To date, sesamoids are thought to develop inside tendons in response to mech...

1839 WILLIAM WILSON Edgar

(1809-49)-American poet, short-story writer, and critic who is best known for his tales of ratiocination, his fantastical horror stories, and his genre-founding detective stories. Poe, whose cloudy personal life is a virtual legend, considered himself primarily a poet. William Wilson (1839)-A tale about a man's struggle with his conscience — an allegory in which William Wilson meets William Wil...

James Hamilton, the younger (1767–1839).